文件名称：肿瘤微环境缺氧和酸度的原因和后果
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更新时间：2024-07-19 13:00:18
学术 论文
Causes and consequences of hypoxia and acidity in tumour microenvironments Causes and consequences of hypoxia and acidity in tumour microenvironments J.R. Griffiths The first major discovery about the physiology and biochem- istry of tumoursÐby Otto Warburg in the early 1920sÐwas the unusual amount of acid that they produced. Even in the presence of oxygen, solid cancers preferentially obtain their energy by converting glucose to lactic acid, by glycolysis. Warburg came to believe that h