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文件名称:细胞死亡:自身免疫的触发因素?
文件大小:174KB
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更新时间:2021-06-29 18:00:59
学术 论文
Cell death: a trigger of autoimmunity?
Cell death:
a trigger of autoimmunity?
R.J.T. Rodenburg, J.M.H. Raats, G.J.M. Pruijn,
and W.J. van Venrooij*
Summary
Systemic autoimmune diseases are characterized by the
production of antibodies against a broad range of self-
antigens. Recent evidence indicates that the majority of
these autoantigens are modified in various ways during
cell death. This has led to the hypothesis that the
primary immune response in the development of auto-
immunity is dir