文件名称:EGF 受体:运输和信号传递的纽带
文件大小:183KB
文件格式:PDF
更新时间:2024-07-19 11:11:39
学术 论文
The EGF receptor: a nexus for trafficking and signaling The EGF receptor: a nexus for trafficking and signaling Graham Carpenter Summary Ligand binding to the EGF receptor initiates both the activation of mitogenic signal transduction pathways plus trafficking events that relocalize the receptor on the cell surface and within intracellular compartments. The trafficking compartments include caveolae, clathrin- coated pits, and various endosome populations prior to receptor degradation in lysos