The puzzle of PCNA's many partners

时间:2024-07-19 13:30:11
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The puzzle of PCNA's many partners The puzzle of PCNA's many partners Emma Warbrick Summary The identification of proteins that interact with proliferat- ing cell nuclear antigen (PCNA) has recently been a rapidly expanding field of discovery. PCNA is involved in many aspects of DNA replication and processing, form- ing a sliding platform that can mediate the interaction of proteins with DNA. It is striking that many proteins bind to PCNA through a small region containing a conserved motif; t


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