DNA polymerases and SOS mutagenesis: can one reconcile the biochemical and genetic data?

时间:2024-07-19 14:29:47
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DNA polymerases and SOS mutagenesis: can one reconcile the biochemical and genetic data? DNA polymerases and SOS mutagenesis: can one reconcile the biochemical and genetic data? Bryn Bridges Summary Until recently, it had been concluded from genetic evidence that DNA polymerase III (Pol III, the main replicative polymerase in E. coli) was also responsible for mutagenic translesion synthesis on damaged tem- plates, albeit under the influence of inducible proteins UmuD 0 and UmuC. Now it appear


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