Deceiving appearances: signaling by "dead" and "fractured" receptor protein-tyrosine kinases

时间:2024-07-19 15:40:00
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文件名称:Deceiving appearances: signaling by "dead" and "fractured" receptor protein-tyrosine kinases

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更新时间:2024-07-19 15:40:00

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Deceiving appearances: signaling by "dead" and "fractured" receptor protein-tyrosine kinases Deceiving appearances: signaling by ``dead'' and ``fractured'' receptor protein-tyrosine kinases Michael Kroiher,1 Michael A. Miller,2 and Robert E. Steele3* Summary The mechanisms by which most receptor protein-tyro- sine kinases (RTKs) transmit signals are now well established. Binding of ligand results in the dimerization of receptor monomers followed by transphosphorylation of tyrosine residues wi


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