虽然我们现在完全没有甲基化的数据,但还是可以了解一下。
什么是DNA甲基化,与组蛋白修饰有什么联系?
DNA Methylation and Its Basic Function
表观的定义就是DNA序列不变、表型变了。最重要的就是DNA的修饰(甲基化)和组蛋白的修饰(chip-seq里面的那几种)
为什么说甲基化比SNP在早筛方面要靠谱得多?
Pan-Cancer Landscape of Aberrant DNA Methylation across Human Tumors
New England Biolabs® Launches NEBNext® Enzymatic Methyl-seq (EM-seq™) for Bisulfite-Free Methylation Analysis
This new enzyme-based system allows scientists to accurately and sensitively assess DNA methylation without bisulfite treatment, for epigenetics research.
亚硫酸氢盐很快将成为过去时
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