1、重新安装office 2003，在安装的过程中选择自定义安装->选择高级，进行下一步，在offiec工具选项中，选择.net framework编程支持。
2、如果还是有问题，可以从开发机器上的C:/Program Files/Microsoft Visual Studio 9.0/Visual Studio Tools for Office/PIA/Office11目录将Microsoft.Office.Interop.Excel.dll拷贝到bin目录
通过以上骤问题应该可以解决。
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